Search Ontology:
ChEBI
vatalanib
- Term ID
- CHEBI:90620
- Synonyms
-
- CGP 79787
- CGP-79787
- CGP79787
- N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
- N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
- N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
- PTK 787
- PTK-787
- PTK/ZK
- PTK787
- vatalanib
- ZK-232934
- Definition
- A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.
- References
-
- cas:212141-54-3
- drugbank:DB04879
- kegg.drug:D06285
- lincs.smallmolecule:LSM-5774
- pubmed:16882767
- pubmed:21617019
- pubmed:22197613
- pubmed:22664478
- pubmed:22910317
- pubmed:23488610
- pubmed:23700288
- pubmed:24449400
- pubmed:24799063
- pubmed:24838014
- pubmed:24939212
- pubmed:25340839
- pubmed:26206183
- pubmed:26403354
- reaxys:8638800
- wikipedia.en:Vatalanib
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from vatalanib
Phenotype where environments contain vatalanib
Phenotype modified by environments containing vatalanib
Phenotype affecting vatalanib
Human Disease Model