ZSTK-474

Term ID

CHEBI:90545

Synonyms

• 1-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-2-(difluoromethyl)-1H-benzimidazole
• 2-(2-difluoromethylbenzimidazol-1-yl)-4,6-bis(morpholino)-1,3,5-triazine
• 2-(2-difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine
• 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole
• 4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
• ZSTK 474
• ZSTK474

Definition

A triamino-1,3,5-triazine that is 1,3,5-triazine in which two of the hydrogens have been replaced by morpholin-4-yl groups while the third hydrogen has been replaced by a 2-(difluoromethyl)benzimidazol-1-yl group. It is an inhibitor of phosphatidylinositol 3-kinase.

References

• cas:475110-96-4
• lincs.smallmolecule:LSM-1053
• pdb-ccd:ZS4
• pubmed:16622124
• pubmed:17711503
• pubmed:19094964
• pubmed:19144509
• pubmed:19182393
• pubmed:20081827
• pubmed:20482767
• pubmed:20729870
• pubmed:21352422
• pubmed:21993922
• pubmed:22088482
• pubmed:22349137
• pubmed:23812078
• pubmed:24204196
• pubmed:24297065
• pubmed:24821574
• pubmed:24844601
• pubmed:25483727
• pubmed:26081844
• reaxys:11677260

Ontology

ChEBI  ( EBI )