N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Term ID

CHEBI:90544

Synonyms

G6A
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-carboxamide
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Definition

A member of the class of biphenyls that is biphenyl in which one of the phenyl groups is substituted at positions 2and 4 by a methyl and a 5-methyl-1,3,4-oxadiazol-2-yl groups, respectively, while the other phenyl group is substituted at positions 2 and 5 by a methyl and an N-(cyclopropyl)aminocarbohyl group, respectively. An inhibitor of p38-alpha MAP kinase.

References

DrugBank:DB07811
PDBeChem:G6A
PMID:18789685
Reaxys:12234786

Ontology

ChEBI ( EBI )

Relationships

is a type of: 1,3,4-oxadiazoles biphenyls cyclopropanes monocarboxylic acid amide ring assembly

1,3,4-oxadiazoles biphenyls cyclopropanes monocarboxylic acid amide ring assembly Show first 5 Terms
has_role: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Phenotype where environments contain N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Phenotype modified by environments containing N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide

Human Disease Model