Search Ontology:
ChEBI
PQIP
- Term ID
- CHEBI:90536
- Synonyms
-
- 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
- Definition
- A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazin-8-amine carrying additional 2-phenylquinolin-7-yl and 3-(4-methylpiperazin-1-yl)cyclobutyl groups at positions 1 and 3 respectively. It is an inhibitor of insulin growth factor 1 receptor (IGF-1 receptor, IGFR1R) tyrosine kinase.
- References
-
- pdb-ccd:D94
- pubmed:17671083
- pubmed:18566589
- pubmed:20943761
- pubmed:21850397
- pubmed:22101930
- pubmed:23239200
- reaxys:12423292
- reaxys:12923638
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from PQIP
Phenotype where environments contain PQIP
Phenotype modified by environments containing PQIP
Phenotype affecting PQIP
Human Disease Model