PI-103

Term ID

CHEBI:90524

Synonyms

3-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol
pi-103
PIK-103

Definition

An organic heterotricyclic compound that is pyrido[3',2':4,5]furo[3,2-d]pyrimidine substituted at positions 2 and 4 by 3-hydroxyphenyl and morpholin-4-yl groups respectively. A dual-kinase inhibitor with anti-cancer properties.

References

cas:371935-74-9
lincs.smallmolecule:LSM-1126
pdb-ccd:X6K
pubmed:20339072
pubmed:23636326
pubmed:24900786
pubmed:25575882
pubmed:25721419
pubmed:25884663
pubmed:26121251
reaxys:11065715

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from PI-103

Phenotype where environments contain PI-103

Phenotype modified by environments containing PI-103

Phenotype affecting PI-103

Human Disease Model