quizartinib

Term ID

CHEBI:90217

Synonyms

1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea
AC 010220
AC 220
AC010220
AC220
N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)urea
quizartinib
quizartinibum
Vanflyta

Definition

A member of the class of phenylureas that is urea in which one of the amino groups has been substituted by a 5-tert-butyl-1,2-oxazol-3-yl group while the other has been substituted by a phenyl group substituted at the para- position by an imidazo[2,1-b][1,3]benzothiazol-2-yl group that, in turn, is substituted at position 7 by a 2-(morpholin-4-yl)ethoxy group.

References

cas:950769-58-1
hmdb:HMDB0257064
kegg.drug:D09955
lincs.smallmolecule:LSM-1037
pdb-ccd:P30
pubmed:19654408
pubmed:22875611
pubmed:23412931
pubmed:23497317
pubmed:23967177
pubmed:24070241
pubmed:24518522
pubmed:24883179
pubmed:25145428
pubmed:25775444
pubmed:25837374
pubmed:25847190
pubmed:29212189
pubmed:30997851
pubmed:31114157
pubmed:32772726
pubmed:33415416
pubmed:34490088
pubmed:35680789
pubmed:36473282
pubmed:37116523
pubmed:37145493
pubmed:37245251
pubmed:37253972
pubmed:37698367
pubmed:37715270
pubmed:37741898
pubmed:37871118
pubmed:37935978
pubmed:37945814
pubmed:38051808
pubmed:38231480
pubmed:38284515
reaxys:12981016
wikipedia.en:Quizartinib

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from quizartinib

Phenotype where environments contain quizartinib

Phenotype modified by environments containing quizartinib

Phenotype affecting quizartinib

Human Disease Model