Search Ontology:
ChEBI
tacedinaline
- Term ID
- CHEBI:90195
- Synonyms
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- 4-(Acetylamino)-N-(2-aminophenyl)benzamide
- 4-acetamido-N-(2-aminophenyl)benzamide
- Acetyldinaline
- C.I. 994
- CI 994
- CI-994
- N-acetyldinaline
- tacedinalina
- tacedinaline
- Definition
- A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
- References
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- CAS:112522-64-2
- KEGG:D05988
- LINCS:LSM-19036
- PMID:25827403
- PMID:26365427
- Reaxys:8422586
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_functional_parent
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- has_role
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Phenotype
Phenotype resulting from tacedinaline
Phenotype where environments contain tacedinaline
Phenotype modified by environments containing tacedinaline
Human Disease Model