Search Ontology:
ChEBI

tacedinaline

Term ID
CHEBI:90195
Synonyms
  • 4-(Acetylamino)-N-(2-aminophenyl)benzamide
  • 4-acetamido-N-(2-aminophenyl)benzamide
  • Acetyldinaline
  • C.I. 994
  • CI 994
  • CI-994
  • N-acetyldinaline
  • tacedinalina
  • tacedinaline
Definition
A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from tacedinaline
Phenotype where environments contain tacedinaline
Phenotype modified by environments containing tacedinaline
Human Disease Model