Search Ontology:
ChEBI
rofecoxib
- Term ID
- CHEBI:8887
- Synonyms
-
- 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
- 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
- 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
- Definition
- A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke.
- References
-
- CAS:162011-90-7
- DrugBank:DB00533
- Drug_Central:2397
- Ontology
- ChEBI ( EBI )
- has_role
- is a type of
Phenotype
Phenotype resulting from rofecoxib
Phenotype where environments contain rofecoxib
Phenotype modified by environments containing rofecoxib
No data available
Phenotype affecting rofecoxib
Human Disease Model