BMS-754807

Term ID

CHEBI:88339

Synonyms

1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-prolinamide
BMS 754807

Definition

A pyrrolotriazine that is pyrrolo[2,1-f][1,2,4]triazine which is substituted at position 2 by the pyrrolidine nitrogen of (2S)-N-(6-fluoropyridin-3-yl)-2-methylprolinamide, and at position 4 by a (5-cyclopropyl-1H-pyrazol-3-yl)amino group. It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: pyrazoles pyridines pyrrolidines pyrrolotriazine

pyrazoles pyridines pyrrolidines pyrrolotriazine Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor

antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from BMS-754807

Phenotype where environments contain BMS-754807

Phenotype modified by environments containing BMS-754807

Human Disease / Model Data

Citations