BMS-754807

Term ID

CHEBI:88339

Synonyms

• 1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-prolinamide
• BMS 754807

Definition

A pyrrolotriazine that is pyrrolo[2,1-f][1,2,4]triazine which is substituted at position 2 by the pyrrolidine nitrogen of (2S)-N-(6-fluoropyridin-3-yl)-2-methylprolinamide, and at position 4 by a (5-cyclopropyl-1H-pyrazol-3-yl)amino group. It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases.

References

• lincs.smallmolecule:LSM-6218
• pdb-ccd:EBI
• pubmed:19996272
• pubmed:20807811
• pubmed:23047891
• pubmed:25527633
• pubmed:25748921

Ontology

ChEBI  ( EBI )