Search Ontology:
ChEBI

4,6-dioxoheptanoic acid

Term ID
CHEBI:87897
Synonyms
  • 4,6-dioxoheptanoic acid
  • succinylacetone
Definition
A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
References
  • cas:51568-18-4
  • hmdb:HMDB0000635
  • patent:US2011201539
  • pdb-ccd:SHU
  • pubmed:10073910
  • pubmed:12052898
  • pubmed:16414314
  • pubmed:16448836
  • pubmed:17133337
  • pubmed:20351174
  • pubmed:22455637
  • pubmed:22456946
  • pubmed:22521492
  • pubmed:22906829
  • pubmed:25066104
  • pubmed:2889780
  • reaxys:2436097
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from 4,6-dioxoheptanoic acid
Phenotype where environments contain 4,6-dioxoheptanoic acid
Phenotype modified by environments containing 4,6-dioxoheptanoic acid
Phenotype affecting 4,6-dioxoheptanoic acid
Human Disease Model