Search Ontology:
ChEBI

ramipril

Term ID
CHEBI:8774
Synonyms
  • (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
  • (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
  • Altace (TN)
  • Ramipril
  • Ramiprilum
  • Tritace
Definition
A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
References
  • cas:87333-19-5
  • drugbank:DB00178
  • drugcentral:2356
  • hmdb:HMDB0014324
  • kegg.drug:D00421
  • lincs.smallmolecule:LSM-5950
  • pubmed:11095026
  • pubmed:11575208
  • pubmed:12076194
  • pubmed:12768220
  • pubmed:15110900
  • pubmed:16144510
  • pubmed:16734081
  • pubmed:17004100
  • pubmed:17192135
  • pubmed:17496463
  • pubmed:17903031
  • pubmed:20122169
  • pubmed:22799880
  • pubmed:23557551
  • pubmed:23713675
  • pubmed:23747952
  • pubmed:23842688
  • pubmed:23842829
  • pubmed:23951921
  • pubmed:24048485
  • pubmed:24090393
  • pubmed:24191305
  • pubmed:24397981
  • pubmed:24435506
  • pubmed:24452090
  • pubmed:24509355
  • reaxys:4214464
  • vsdb:1888
  • wikipedia.en:Ramipril
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from ramipril
Phenotype where environments contain ramipril
Phenotype modified by environments containing ramipril
Phenotype affecting ramipril
Human Disease Model