pyrantel

Term ID

CHEBI:8654

Synonyms

• 1-methyl-2-[(E)-2-(2-thienyl)vinyl]-1,4,5,6-tetrahydropyrimidine
• pirantel
• pyrantel
• pyrantelum

Definition

A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.

References

• cas:15686-83-6
• drugcentral:2999
• kegg.compound:C07409
• kegg.drug:D08451
• patent:BE658987
• patent:US3502661
• pubmed:20307935
• pubmed:21689886
• pubmed:2619378
• pubmed:5124439
• pubmed:552733
• pubmed:7402460
• reaxys:518505
• wikipedia.en:Pyrantel

Ontology

ChEBI  ( EBI )

Resources

CTD