lenvatinib

Term ID

CHEBI:85994

Synonyms

• 4-(3-Chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
• 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide
• E 7080
• E7080
• lenvatinib
• UNII-EE083865G2

Definition

A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine.

References

• cas:417716-92-8
• drugcentral:4942
• kegg.drug:D09919
• pdb-ccd:LEV
• pubmed:25240824
• pubmed:25458359
• pubmed:25589937
• pubmed:25600977
• pubmed:25616432
• pubmed:25625428
• pubmed:25671254
• pubmed:25720434
• pubmed:25795101
• pubmed:25859118
• pubmed:25913680
• pubmed:25974026
• pubmed:26008987
• pubmed:26026266
• reaxys:12096874
• wikipedia.en:Lenvatinib

Ontology

ChEBI  ( EBI )