lenvatinib

Term ID

CHEBI:85994

Synonyms

4-(3-Chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide
E 7080
E7080
lenvatinib
UNII-EE083865G2

Definition

A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amide aromatic ether cyclopropanes monocarboxylic acid amide monochlorobenzenes ... Show All 7 Terms

aromatic amide aromatic ether cyclopropanes monocarboxylic acid amide monochlorobenzenes phenylureas quinolines Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor fibroblast growth factor receptor antagonist orphan drug vascular endothelial growth factor receptor antagonist

antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor fibroblast growth factor receptor antagonist orphan drug vascular endothelial growth factor receptor antagonist Show first 5 Terms
inverse is_conjugate_acid_of: lenvatinib(1+)

lenvatinib(1+) Show first 5 Terms
is_conjugate_base_of: lenvatinib(1+)

lenvatinib(1+) Show first 5 Terms

Phenotype

Phenotype resulting from lenvatinib

Phenotype where environments contain lenvatinib

Phenotype modified by environments containing lenvatinib

Human Disease / Model Data