Search Ontology:
ChEBI
panobinostat
- Term ID
- CHEBI:85990
- Synonyms
-
- (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide
- LBH 589
- LBH589
- panobinostat
- Definition
- A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma.
- References
-
- cas:404950-80-7
- drugcentral:4682
- kegg.drug:D10319
- pubmed:25305451
- pubmed:25377157
- pubmed:25410127
- pubmed:25458954
- pubmed:25572329
- pubmed:25608569
- pubmed:25612941
- pubmed:25628765
- pubmed:25710456
- pubmed:25802326
- pubmed:25837990
- pubmed:25870990
- pubmed:25904215
- pubmed:25939707
- pubmed:25944617
- pubmed:26000292
- pubmed:26030093
- pubmed:26051506
- reaxys:12257756
- wikipedia.en:Panobinostat
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from panobinostat
Phenotype where environments contain panobinostat
Phenotype modified by environments containing panobinostat
Phenotype affecting panobinostat
Human Disease Model