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ChEBI

ivabradine

Term ID
CHEBI:85966
Synonyms
  • 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
  • ivabradine
  • S 16257
  • S 16257-2
  • S-16257
  • S-16257-2
Definition
A member of the class of benzazepines that is 7,8-dimethoxy-1,3,4,5-tetrahydro-3-benzazepin-2-one in which the amide hydrogen is replaced by a [{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl} group. Used (as its hydrochloride salt) to treat patients with angina who have intolerance to beta blockers and/or heart failure.
References
  • cas:155974-00-8
  • drugcentral:3312
  • kegg.drug:D07165
  • pubmed:25158669
  • pubmed:25179314
  • pubmed:25240447
  • pubmed:25346368
  • pubmed:25350985
  • pubmed:25636072
  • pubmed:25656911
  • pubmed:25687888
  • pubmed:25700807
  • pubmed:25706659
  • pubmed:25733317
  • pubmed:25801408
  • pubmed:25809454
  • pubmed:25839989
  • pubmed:25911606
  • pubmed:25926678
  • pubmed:25953938
  • pubmed:25968495
  • pubmed:25982136
  • pubmed:25986146
  • reaxys:8366413
  • wikipedia.en:Ivabradine
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from ivabradine
Phenotype where environments contain ivabradine
Phenotype modified by environments containing ivabradine
Phenotype affecting ivabradine
Human Disease Model