lixisenatide

Term ID

CHEBI:85662

Synonyms

• Adlyxin
• AQVE-10010
• AVE 0010
• AVE0010
• des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide
• DesPro38Exendin-4(1-39)-Lys6-NH2
• H-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPSKKKKKK-NH2
• H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2
• H-L-His-Gly-L-Glu-Gly-L-Thr-L-Phe-L-Thr-L-Ser-L-Asp-L-Leu-L-Ser-L-Lys-L-Gln-L-Met-L-Glu-L-Glu-L-Glu-L-Ala-L-Val-L-Arg-L-Leu-L-Phe-L-Ile-L-Glu-L-Trp-L-Leu-L-Lys-L-Asn-Gly-Gly-L-Pro-L-Ser-L-Ser-Gly-L-Ala-L-Pro-L-Pro-L-Ser-L-Lys-L-Lys-L-Lys-L-Lys-L-Lys-L-Lys
• L-histidylglycyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L
• lixisenatida
• lixisenatide
• lixisenatidum
• Lyxumia
• ZP 10
• ZP10A peptide

Definition

A forty-four membered polypeptide consisting of L-His, Gly, L-Glu, Gly, L-Thr, L-Phe, L-Thr, L-Ser, L-Asp, L-Leu, L-Ser, L-Lys, L-Gln, L-Met, L-Glu, L-Glu, L-Glu, L-Ala, L-Val, L-Arg, L-Leu, L-Phe, L-Ile, L-Glu, L-Trp, L-Leu, L-Lys, L-Asn, Gly, Gly, LPro, L-Ser, L-Ser, Gly, L-Ala, L-Pro, L-Pro, L-Ser, L-Lys, L-Lys, L-Lys, L-Lys, L-Lys, and L-Lys-NH₂ residues joined in sequence. Used as an adjunct to diet and exercise for the treatment of adults with type II diabetes.

References

• cas:320367-13-3
• drugcentral:4815
• kegg.drug:D09729
• pubmed:19629885
• pubmed:21391833
• pubmed:23537041
• pubmed:23558600
• pubmed:23825925
• pubmed:23992745
• pubmed:24086950
• pubmed:24122776
• pubmed:24363554
• pubmed:24373190
• pubmed:24476092
• pubmed:24583037
• pubmed:24641271
• pubmed:24683832
• pubmed:24876548
• pubmed:25012990
• pubmed:25027491
• pubmed:25055456
• pubmed:25066229
• pubmed:25107586
• pubmed:25115916
• pubmed:25119443
• pubmed:25130920
• pubmed:25195184
• pubmed:25773712
• pubmed:25802728
• pubmed:25853868
• pubmed:25887358
• pubmed:25965710
• pubmed:26342556
• pubmed:26423184
• pubmed:26537183
• pubmed:26594250
• pubmed:26630143
• pubmed:26701217
• pubmed:26770666
• pubmed:26787264
• pubmed:26981945
• pubmed:26981946
• pubmed:26981947
• pubmed:27092017
• pubmed:27222510
• pubmed:27252787
• pubmed:27267268
• pubmed:27284114
• pubmed:27310712
• pubmed:27311491
• pubmed:27319011
• pubmed:27341040
• reaxys:23952540
• wikipedia.en:Lixisenatide

Ontology

ChEBI  ( EBI )