Search Ontology:
ChEBI

palonosetron hydrochloride

Term ID
CHEBI:85157
Synonyms
  • (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one--hydrogen chloride (1/1)
  • (3S)-3-[(3aS)-1-oxo-3a,4,5,6-tetrahydro-1H-benzo[de]isoquinolin-2(3H)-yl]-1-azabicyclo[2.2.2]octan-1-ium chloride
  • Aloxi
Definition
A hydrochloride obtained by combining palonosetron with one molar equivalent of hydrogen chloride; an antiemetic used in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.
References
  • cas:135729-62-3
  • drugbank:DB00377
  • kegg.drug:D05343
  • pubmed:23354552
  • pubmed:23414148
  • pubmed:23614072
  • pubmed:23737892
  • pubmed:23984894
  • pubmed:24128813
  • pubmed:24363841
  • pubmed:24709591
  • pubmed:24772303
  • pubmed:25105088
  • pubmed:25165427
  • reaxys:21177207
  • reaxys:6641153
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from palonosetron hydrochloride
Phenotype where environments contain palonosetron hydrochloride
Phenotype modified by environments containing palonosetron hydrochloride
Phenotype affecting palonosetron hydrochloride
Human Disease Model