sofosbuvir

Term ID

CHEBI:85083

Synonyms

GI 7977
GS-7977
isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate
PSI 7977
PSI-7977
Sovaldi

Definition

A nucleotide conjugate that is used in combination with ledipasvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: isopropyl ester L-alanyl ester nucleotide conjugate organofluorine compound phosphoramidate ester

isopropyl ester L-alanyl ester nucleotide conjugate organofluorine compound phosphoramidate ester Show first 5 Terms
has_functional_parent: uridine 5'-monophosphate

uridine 5'-monophosphate Show first 5 Terms
has_role: antiviral drug hepatitis C protease inhibitor prodrug

antiviral drug hepatitis C protease inhibitor prodrug Show first 5 Terms
inverse has_part: Epclusa Harvoni

Epclusa Harvoni Show first 5 Terms

Phenotype

Phenotype resulting from sofosbuvir

Phenotype where environments contain sofosbuvir

Phenotype modified by environments containing sofosbuvir

Human Disease Model