dapagliflozin

Term ID

CHEBI:85078

Synonyms

(1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
BMS 512148
BMS-512148
dapagliflozin

Definition

A C-glycosyl comprising β-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-(4-ethoxybenzyl)phenyl group. Used (in the form of its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes.

References

cas:461432-26-8
drugbank:DB06292
drugcentral:4304
kegg.drug:D08897
pmc:PMC10706647
pubmed:20509715
pubmed:23724409
pubmed:24840612
pubmed:25200570
pubmed:25351341
pubmed:25418019
pubmed:25421015
pubmed:25438821
pubmed:25516459
pubmed:25557661
pubmed:25560982
pubmed:25592197
pubmed:25609661
pubmed:25648671
pubmed:25671589
pubmed:25678954
pubmed:25688892
pubmed:25688893
pubmed:25694411
pubmed:25710563
pubmed:30000030
pubmed:32454718
pubmed:33859839
pubmed:35272683
pubmed:37113469
pubmed:37549309
pubmed:37664712
pubmed:37758208
pubmed:37895841
pubmed:37931629
pubmed:37936747
pubmed:37979161
pubmed:38017482
pubmed:38031729
pubmed:38044448
pubmed:38094412
pubmed:38097862
pubmed:38117458
pubmed:38124408
pubmed:38128857
pubmed:38133155
pubmed:38137545
pubmed:38170280
pubmed:38171497
pubmed:38171852
pubmed:38185119
pubmed:38220410
reaxys:11966426
wikipedia.en:Dapagliflozin

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from dapagliflozin

Phenotype where environments contain dapagliflozin

Phenotype modified by environments containing dapagliflozin

Phenotype affecting dapagliflozin

Human Disease Model