probucol

Term ID

CHEBI:8427

Synonyms

4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol)
4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol)
Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
Biphenabid
Bisbid
Bisphenabid
DH-581
Lesterol
Lorelco
Lurselle
probucol
probucolum
Serterol
Superlipid

Definition

A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

References

cas:23288-49-5
drugbank:DB01599
drugcentral:2269
hmdb:HMDB0015537
kegg.compound:C07373
kegg.drug:D00476
lincs.smallmolecule:LSM-3617
patent:CN101423484
patent:CN101455842
patent:CN102973535
patent:FR1561853
patent:US3576883
patent:US3862332
pubmed:22305809
pubmed:23107872
pubmed:23167559
pubmed:23334712
pubmed:23363981
pubmed:23378294
pubmed:23443157
pubmed:23741215
reaxys:2026253
wikipedia.en:Probucol

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from probucol

Phenotype where environments contain probucol

Phenotype modified by environments containing probucol

Phenotype affecting probucol

Human Disease Model