tubulozole

Term ID

CHEBI:83928

Synonyms

• Ethyl (+-)-cis-p-(((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-p-ylmethylthio)thio))carbanilate
• R 46846
• rac-ethyl [4-({[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}sulfanyl)phenyl]carbamate
• rac-ethyl [4-({[(2S,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}sulfanyl)phenyl]carbamate
• tubulazole
• tubulozol
• tubulozole
• Tubulozole C
• tubulozolum

Definition

A racemate comprising equimolar amounts of (2R,4R)- and (2S,4S)-tubulozole. A synthetic anticancer drug that interferes with the structure and function of microtubules in both interphase and mitotic cells.

References

• cas:84697-22-3
• pubmed:12910417
• pubmed:1490278
• pubmed:2221861
• pubmed:2912940
• pubmed:2957009
• pubmed:3967244
• pubmed:3997412
• pubmed:8233593
• pubmed:8475033
• reaxys:8803875

Ontology

ChEBI  ( EBI )

Resources

CTD