Search Ontology:
ChEBI

pravastatin sodium

Term ID
CHEBI:8361
Synonyms
  • sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate
Definition
An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.
References
  • cas:81131-70-6
  • drugbank:DB00175
  • hmdb:HMDB0005022
  • kegg.drug:D00893
  • pubmed:1425808
  • pubmed:1680649
  • pubmed:1926908
  • reaxys:4224939
  • wikipedia.en:Parvaststin
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from pravastatin sodium
Phenotype where environments contain pravastatin sodium
Phenotype modified by environments containing pravastatin sodium
Phenotype affecting pravastatin sodium
Human Disease Model