fosamprenavir

Term ID

CHEBI:82941

Synonyms

• (3S)-tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-phenyl-3-(phosphonooxy)butan-2-yl]carbamate
• FOS-APV
• fosamprenavir

Definition

A sulfonamide with a structure based on that of sulfanilamide substituted on the sulfonamide nitrogen by a (2R,3S)-4-phenyl-2-(phosphonooxy)-3-({[(3S)-tetrahydrofuran-3-yloxy]carbonyl}amino)butyl group. It is a pro-drug of the HIV protease inhibitor and antiretroviral drug amprenavir.

References

• cas:226700-79-4
• drugbank:DB01319
• drugcentral:1240
• hmdb:HMDB0015416
• kegg.drug:D02497
• pubmed:16890834
• pubmed:22100576
• pubmed:23314414
• pubmed:23811744
• pubmed:24741696
• pubmed:24929949
• pubmed:25017682
• pubmed:25155604
• reaxys:9824450
• wikipedia.en:Fosamprenavir

Ontology

ChEBI  ( EBI )