mertansine

Term ID

CHEBI:82755

Synonyms

• (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1(10,14).0(3,5)]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate
• DM 1
• DM1
• maytansinoid DM 1
• maytansinoid DM1
• N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine

Definition

An organic heterotetracyclic compound and 19-membered macrocyclic lactam that is maytansine in which one of the hydrogens of the terminal N-acetyl group is replaced by a sulfanylmethyl group.

References

• cas:139504-50-0
• kegg.compound:C20259
• pubmed:23798344
• pubmed:24389179
• pubmed:24623670
• pubmed:24887180
• reaxys:10753281
• wikipedia.en:Mertansine

Ontology

ChEBI  ( EBI )