tedizolid

Term ID

CHEBI:82717

Synonyms

(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
DA 7157
DA-7157
tedizolid
Torezolid
TR 700
TR-700

Definition

A member of the class of pyridines that is pyridine which is substituted by a 2-methyl-2H-tetrazol-5-yl group at position 2 and by a 2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl group at position 5. It is used as its phosphate pro-drug used for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.

References

cas:856866-72-3
kegg.drug:D09685
pubmed:23571550
pubmed:23589680
pubmed:23926058
pubmed:24343828
pubmed:24343829
pubmed:24343830
pubmed:24343832
pubmed:24343833
pubmed:24688035
pubmed:24708819
pubmed:24875463
pubmed:24909499
pubmed:24989138
pubmed:25136024
pubmed:25136028
pubmed:25136252
pubmed:25210412
pubmed:25238753
pubmed:25246392
pubmed:25266820
reaxys:10589936
wikipedia.en:Tedizolid

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from tedizolid

Phenotype where environments contain tedizolid

Phenotype modified by environments containing tedizolid

Phenotype affecting tedizolid

Human Disease Model