idelalisib

Term ID

CHEBI:82701

Synonyms

• 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one
• 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one
• CAL-101
• GS-1101
• ZYDELIG

Definition

A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia.

References

• cas:870281-82-6
• drugcentral:4878
• lincs.smallmolecule:LSM-1205
• pubmed:24376763
• pubmed:24450857
• pubmed:24450858
• pubmed:24463402
• pubmed:24615776
• pubmed:24615777
• pubmed:24615778
• pubmed:24619588
• pubmed:24659719
• pubmed:24795031
• pubmed:25093123
• pubmed:25187123
• pubmed:25274697
• reaxys:12464214
• wikipedia.en:Idelalisib

Ontology

ChEBI  ( EBI )