suvorexant

Term ID

CHEBI:82698

Synonyms

• [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone
• BELSOMRA
• MK 4305
• MK-4305
• MK4305
• suvorexant

Definition

An aromatic amide obtained by formal condensation of the carboxy group of 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid with the secondary amino group of 5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole. An orexin receptor antagonist used for the management of insomnia.

References

• cas:1030377-33-3
• drugcentral:4881
• kegg.drug:D10082
• pubmed:23372274
• pubmed:23692283
• pubmed:24368893
• pubmed:24488306
• pubmed:24550770
• pubmed:24680372
• pubmed:24757363
• pubmed:25167596
• pubmed:25197807
• pubmed:25227290
• pubmed:25231363
• pubmed:25291725
• pubmed:25299902
• reaxys:18339082
• wikipedia.en:Suvorexant

Ontology

ChEBI  ( EBI )