monascin

Term ID

CHEBI:82621

Synonyms

(3S,3aR,9aR)-3-hexanoyl-9a-methyl-6-[(1E)-prop-1-en-1-yl]-3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
monascusone B

Definition

An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl and methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of carcinogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: alpha,beta-unsaturated ketone gamma-lactone organic heterotricyclic compound polyketide

alpha,beta-unsaturated ketone gamma-lactone organic heterotricyclic compound polyketide Show first 5 Terms
has_role: antilipemic drug antineoplastic agent fungal metabolite PPARgamma agonist

antilipemic drug antineoplastic agent fungal metabolite PPARgamma agonist Show first 5 Terms

Phenotype

Phenotype resulting from monascin

Phenotype where environments contain monascin

Phenotype modified by environments containing monascin

Human Disease / Model Data

Citations