pioglitazone

Term ID

CHEBI:8228

Synonyms

• (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
• 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
• pioglitazona
• Pioglitazone
• pioglitazonum

Definition

A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

References

• Beilstein:3595485
• CAS:111025-46-8
• Chemspider:4663
• DrugBank:DB01132
• Drug_Central:2179
• HMDB:HMDB0015264
• KEGG:C07675
• KEGG:D08378
• LINCS:LSM-1592
• PMID:12879407
• PMID:14522601
• PMID:17628757
• PMID:18215232
• PMID:20797618
• PMID:27842070
• PMID:33798599
• PMID:33864097
• PMID:33983968
• PMID:33995271
• PMID:34006325
• PMID:34009030
• Patent:EP193256
• Patent:US4687777
• Reaxys:3595485
• Wikipedia:Pioglitazone

Ontology

ChEBI  ( EBI )

Resources

CTD