substance P

Term ID

CHEBI:80308

Synonyms

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide
RPKPQQFFGLM-amide
RPKPQQFFGLM-NH2

Definition

A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission.

References

cas:33507-63-0
foodb.food:FDB002259
hmdb:HMDB0001897
kegg.compound:C16094
patent:US2010190722
pubmed:16729222
pubmed:28474564
pubmed:30935032
pubmed:32634530
pubmed:33688239
pubmed:34017371
pubmed:34915568
pubmed:35054936
pubmed:35269726
pubmed:35402619
pubmed:35485451
pubmed:35507035
pubmed:35525773
pubmed:35779793
pubmed:35806893
pubmed:35820276
pubmed:35856812
pubmed:35884599
pubmed:35904495
pubmed:35948329
pubmed:35955767
pubmed:36001730
pubmed:36040535
pubmed:36067981
pubmed:36146768
pubmed:36165925
pubmed:36197354
pubmed:36351068
pubmed:36361972
pubmed:36385363
pubmed:36414415
pubmed:6196797
pubmed:7541689
wikipedia.en:Substance_P

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from substance P

Phenotype where environments contain substance P

Phenotype modified by environments containing substance P

Phenotype affecting substance P

Human Disease Model