penciclovir

Term ID

CHEBI:7956

Synonyms

• 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one
• 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine
• 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine
• 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
• 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
• PCV
• PE2
• penciclovir
• penciclovirum

Definition

A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration.

References

• cas:39809-25-1
• drugbank:DB00299
• drugcentral:2079
• hmdb:HMDB0014444
• kegg.compound:C07417
• kegg.drug:D05407
• lincs.smallmolecule:LSM-5587
• patent:US5075445
• pdb-ccd:PE2
• pubmed:3040998
• reaxys:4501039
• wikipedia.en:Penciclovir

Ontology

ChEBI  ( EBI )