pemoline

Term ID

CHEBI:7953

Synonyms

• 2-amino-5-phenyl-1,3-oxazol-4(5H)-one
• 2-Amino-5-phenyl-4(5H)-oxazolone
• 2-imino-4-keto-5-phenyltetrahydrooxazole
• 2-imino-5-phenyl-4-oxazolidinone
• 5-phenyl-2-imino-4-oxazolidinone
• 5-phenyl-2-imino-4-oxooxazolidine
• 5-phenylisohydantion
• Azoxodon
• Betanamin
• Cylert
• Dantromin
• Deltamine
• Hyton
• Myamin
• Nitan
• Notair
• pemolina
• pemoline
• pemolinum
• pheniminooxazolidinone
• phenylisohydantoin
• phenylpseudohydantoin

Definition

A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

References

• CAS:2152-34-3
• DrugBank:DB01230
• Drug_Central:2075
• KEGG:C07899
• KEGG:D00744
• LINCS:LSM-5159
• PMID:11216184
• PMID:2210262
• PMID:2303976
• PMID:2388127
• PMID:4021028
• PMID:641739
• PMID:772696
• Reaxys:151559
• Wikipedia:Pemoline

Ontology

ChEBI  ( EBI )

Resources

CTD