Search Ontology:
ChEBI
paromomycin
- Term ID
- CHEBI:7934
- Synonyms
-
- (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
- Aminosidin
- aminosidine
- Definition
- An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.
- References
-
- CAS:7542-37-2
- DrugBank:DB01421
- Drug_Central:2067
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- inverse has_functional_parent
- inverse is_conjugate_acid_of
- has_role
- has_functional_parent
- is_conjugate_base_of
- is a type of
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Phenotype
Phenotype resulting from paromomycin
No data available
Phenotype where environments contain paromomycin
| Fish | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|
| mpv17a9; gmc500Tg | chemical treatment by environment: paromomycin, chemical treatment by environment: metronidazole | Fig. 7  from Zhang et al., 2021 |
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Phenotype modified by environments containing paromomycin
| Fish | Modification | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|---|
| mpv17a9; gmc500Tg | ameliorated | chemical treatment by environment: paromomycin, chemical treatment by environment: metronidazole | Fig. 7 from Zhang et al., 2021 |
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Phenotype affecting paromomycin
No data available
Human Disease Model