ascr#5

Term ID

CHEBI:78829

Synonyms

(-)-3-(3'R,5'R-dihydroxy-6'S-methyl-(2H)-tetrahydropyran-2'-yloxy)-propanoic acid
3-[(3,6-dideoxy-alpha-L-arabino-hexopyranosyl)oxy]propanoic acid
3-hydroxypropanoic acid 3-O-alpha-ascarylopyranoside
ascaroside C3

Definition

An ω-hydroxy fatty acid ascaroside obtained by formal condensation of the alcoholic hydroxy group of 3-hydroxypropanoic acid with ascarylopyranose (the α anomer). A major component of the dauer pheromone of the nematode Caenorhabditis elegans, it synergises with ascr#2 and ascr#3 as a population-density signal to promote entry into an alternate larval stage, the nonfeeding and highly persistent dauer diapause.

References

cas:1086696-26-5
pubmed:18791072
pubmed:19174521
pubmed:19346493
pubmed:19349961
pubmed:19496754
pubmed:19545143
pubmed:19665885
pubmed:19797623
pubmed:20135027
pubmed:20151418
pubmed:20713521
pubmed:21423575
pubmed:21849976
pubmed:21959166
pubmed:22239548
pubmed:22253572
pubmed:22503501
pubmed:22665789
pubmed:22701701
pubmed:22920251
pubmed:23689506
reaxys:22233379
smid:ascr%235%0D

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from ascr#5

Phenotype where environments contain ascr#5

Phenotype modified by environments containing ascr#5

Phenotype affecting ascr#5

Human Disease Model