ascr#2

Term ID

CHEBI:78812

Synonyms

(-)-5R-(3'R,5'R-dihydroxy-6'S-methyl-(2H)-tetrahydropyran-2'-yloxy)-2-hexanone
(2R)-5-oxohexan-2-yl 3,6-dideoxy-alpha-L-arabino-hexopyranoside
ascaroside C6
daumone-2

Definition

A hydroxy ketone ascaroside obtained by formal condensation of the hydroxy group of (5R)-5-hydroxyhexan-2-one with ascarylopyranose (the α anomer). It is a major component of the dauer pheromone, used by the nematode Caenorhabditis elegans as a population-density signal to promote entry into an alternate larval stage, the nonfeeding and highly persistent dauer diapause, and also synergises with ascr#3, ascr#4, and ascr#8 in male attraction.

References

cas:946524-24-9
pubmed:17558398
pubmed:18650807
pubmed:18791072
pubmed:19174521
pubmed:19346493
pubmed:19349961
pubmed:19496754
pubmed:19545143
pubmed:19649780
pubmed:19665885
pubmed:19797623
pubmed:19813005
pubmed:20135027
pubmed:20151418
pubmed:20713521
pubmed:20929849
pubmed:21423575
pubmed:21849976
pubmed:21935539
pubmed:21959166
pubmed:22239548
pubmed:22253572
pubmed:22503501
pubmed:22665789
pubmed:22701701
pubmed:22920251
pubmed:23161728
pubmed:23213209
pubmed:23347231
pubmed:23509272
pubmed:23689506
reaxys:19924214
smid:ascr%232%0D

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from ascr#2

Phenotype where environments contain ascr#2

Phenotype modified by environments containing ascr#2

Phenotype affecting ascr#2

Human Disease Model