oxymetazoline

Term ID

CHEBI:7862

Synonyms

• 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
• 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
• 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
• 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
• 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
• oxymetazolina
• oxymetazoline
• oxymetazolinum

Definition

A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked α-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

References

• cas:1491-59-4
• drugbank:DB00935
• drugcentral:2032
• hmdb:HMDB0015070
• kegg.compound:C07363
• kegg.drug:D08322
• lincs.smallmolecule:LSM-2353
• patent:DE1117588
• pubmed:10487000
• pubmed:21177487
• pubmed:23679077
• pubmed:23988443
• pubmed:4003266
• reaxys:886303
• wikipedia.en:Oxymetazoline

Ontology

ChEBI  ( EBI )

Resources

CTD