oxymetazoline

Term ID

CHEBI:7862

Synonyms

2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
oxymetazolina
oxymetazoline
oxymetazolinum

Definition

A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

References

CAS:1491-59-4
DrugBank:DB00935
Drug_Central:2032
HMDB:HMDB0015070
KEGG:C07363
KEGG:D08322
LINCS:LSM-2353
PMID:10487000
PMID:21177487
PMID:23679077
PMID:23988443
PMID:4003266
Patent:DE1117588
Reaxys:886303
Wikipedia:Oxymetazoline

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: carboxamidine imidazolines phenols

carboxamidine imidazolines phenols Show first 5 Terms
has_role: alpha-adrenergic agonist nasal decongestant sympathomimetic agent vasoconstrictor agent

alpha-adrenergic agonist nasal decongestant sympathomimetic agent vasoconstrictor agent Show first 5 Terms
inverse is_conjugate_acid_of: oxymetazoline(1+)

oxymetazoline(1+) Show first 5 Terms
is_conjugate_base_of: oxymetazoline(1+)

oxymetazoline(1+) Show first 5 Terms

Phenotype

Phenotype resulting from oxymetazoline

Phenotype where environments contain oxymetazoline

Phenotype modified by environments containing oxymetazoline

Human Disease Model