apremilast

Term ID

CHEBI:78540

Synonyms

apremilast
apremilastum
CC 10004
CC-10004
CC10004
N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
OTEZLA

Definition

A member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis.

References

cas:608141-41-9
drugcentral:4829
kegg.drug:D08860
pubmed:22910104
pubmed:22984171
pubmed:23030767
pubmed:23569359
pubmed:23588944
pubmed:23663752
pubmed:23986162
pubmed:24072562
pubmed:24592316
pubmed:24595547
pubmed:24702658
pubmed:24797159
pubmed:24846499
pubmed:24852768
pubmed:24869713
pubmed:24882690
pubmed:24962564
pubmed:24979544
pubmed:24997741
pubmed:24998661
pubmed:25027606
pubmed:25050054
pubmed:25054629
reaxys:12446985
wikipedia.en:Apremilast

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from apremilast

Phenotype where environments contain apremilast

Phenotype modified by environments containing apremilast

Phenotype affecting apremilast

Human Disease Model