mastoparan-M

Term ID

CHEBI:78518

Synonyms

Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-NH2
L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide
Mast cell degranulating peptide (Vespa mandarinia)
MP-M

Definition

A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, isoleucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa mandarinia and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: mastoparans peptidyl amide

mastoparans peptidyl amide Show first 5 Terms
has_role: antibacterial agent

antibacterial agent Show first 5 Terms

Phenotype

Phenotype resulting from mastoparan-M

Phenotype where environments contain mastoparan-M

Phenotype modified by environments containing mastoparan-M

Human Disease Model