LRRK2-IN-1

Term ID

CHEBI:78413

Synonyms

2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
LRRK2-IN1
LRRK2IN1

Definition

A member of the class of pyrimidobenzodiazepines that is 5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a 4-[(4-methylpiperazin-1-yl)piperidine-1-carbonyl]-2-methoxyanilino substituent. It is an inhibitor of the Parkinson's disease kinase LRRK2.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine aromatic ether N-acylpiperidine N-alkylpiperazine pyrimidobenzodiazepine ... Show All 7 Terms

aromatic amine aromatic ether N-acylpiperidine N-alkylpiperazine pyrimidobenzodiazepine secondary amino compound tertiary amino compound Show first 5 Terms
has_role: antineoplastic agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

antineoplastic agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from LRRK2-IN-1

Phenotype where environments contain LRRK2-IN-1

Phenotype modified by environments containing LRRK2-IN-1

Human Disease Model