oxiconazole

Term ID

CHEBI:7825

Synonyms

• (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine
• 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime]
• oxiconazol
• oxiconazole
• oxiconazolum
• Ro 13-8996

Definition

An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

References

• cas:64211-45-6
• drugbank:DB00239
• drugcentral:3408
• hmdb:HMDB0014384
• kegg.compound:C08074
• kegg.drug:D08313
• patent:US4550175
• pubmed:15797782
• pubmed:2029718
• pubmed:22569007
• pubmed:23482479
• pubmed:2793313
• pubmed:7037014
• reaxys:6004213
• wikipedia.en:Oxiconazole

Ontology

ChEBI  ( EBI )

Resources

CTD