oxamniquine

Term ID

CHEBI:7819

Synonyms

(+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
(+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
Mansil
oxamniquina
oxamniquine
oxamniquinum
rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
rac-oxamniquine
rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
UK 4271
UK-4271
UK4271
Vansil

Definition

A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.

References

cas:21738-42-1
drugbank:DB01096
hmdb:HMDB0015228
kegg.compound:C07341
kegg.drug:D00460
patent:US3821228
pdb-ccd:OAQ
pubmed:10321028
pubmed:11516919
pubmed:1198006
pubmed:17988075
pubmed:2083150
pubmed:21500322
pubmed:23450530
pubmed:2490562
pubmed:2638729
pubmed:3082231
pubmed:3127959
pubmed:349665
pubmed:4203813
pubmed:4205106
pubmed:4977703
pubmed:734715
pubmed:7767464
pubmed:823880
pubmed:8839672
reaxys:485597
wikipedia.en:Oxamniquine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from oxamniquine

Phenotype where environments contain oxamniquine

Phenotype modified by environments containing oxamniquine

Phenotype affecting oxamniquine

Human Disease Model