oxamniquine

Term ID

CHEBI:7819

Synonyms

• (+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
• (+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
• (+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
• 1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
• 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
• Mansil
• oxamniquina
• oxamniquine
• oxamniquinum
• rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
• rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
• rac-oxamniquine
• rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
• UK 4271
• UK-4271
• UK4271
• Vansil

Definition

A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.

References

• CAS:21738-42-1
• DrugBank:DB01096
• HMDB:HMDB0015228
• KEGG:C07341
• KEGG:D00460
• PDBeChem:OAQ
• PMID:10321028
• PMID:11516919
• PMID:1198006
• PMID:17988075
• PMID:2083150
• PMID:21500322
• PMID:23450530
• PMID:2490562
• PMID:2638729
• PMID:3082231
• PMID:3127959
• PMID:349665
• PMID:4203813
• PMID:4205106
• PMID:4977703
• PMID:734715
• PMID:7767464
• PMID:823880
• PMID:8839672
• Patent:US3821228
• Reaxys:485597
• Wikipedia:Oxamniquine

Ontology

ChEBI  ( EBI )

Resources

CTD