Search Ontology:
ChEBI
dextilidine
- Term ID
- CHEBI:77822
- Synonyms
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- (+)-(1S,2R)-ethyl-2-dimethylamino-1-phenyl-3-cyclohexen-1-carboxylate
- (+)-ethyl trans-2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate
- (1S,2R)-(+)-ethyl-2-dimethylamino-1-phenyl-3-cyclohexen-1-carboxylate
- dextilidina
- dextilidine
- dextilidinum
- ethyl (1S,2R)-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
- Definition
- An ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine).
- References
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- CAS:32447-90-8
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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- inverse has_part
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- inverse is_enantiomer_of
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- is_enantiomer_of
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Show first 5 Terms
Phenotype
Phenotype resulting from dextilidine
Phenotype where environments contain dextilidine
Phenotype modified by environments containing dextilidine
Human Disease Model