Search Ontology:
ChEBI

temafloxacin

Term ID
CHEBI:77788
Synonyms
  • (+-)-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • (+-)-temafloxacin
  • A 62254
  • rac-1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • rac-temafloxacin
  • T 1258
  • temafloxacin
  • temafloxacine
  • temafloxacino
  • temafloxacinum
Definition
A racemate comprising equimolar amounts of (R)- and (S)-temafloxacin. Both enantiomers both exhibit similar pharmacological profiles. Temafloxacin was briefly used (either as the free base or as the hydrochloride salt) as an antibacterial drug but was withdrawn worldwide in 1992 following reports of serious side effects, including severe hypoglycaemia, haemolytic anaemia, liver and kidney dysfunction, anaphylaxis, and death.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from temafloxacin
Phenotype where environments contain temafloxacin
Phenotype modified by environments containing temafloxacin
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.