sulfaphenazole

Term ID

CHEBI:77780

Synonyms

• 1-phenyl-5-sulfanilamidopyrazole
• 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole
• 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
• 5-sulfanilamido-1-phenylpyrazole
• N'-(1-phenylpyrazol-5-yl)sulfanilamide
• N(1)-(1-phenylpyrazol-5-yl)sulfanilamide
• Sulfabid
• sulfafenazol
• sulfaphenazol
• sulfaphenazole
• sulfaphenazolum
• sulphaphenazole

Definition

A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.

References

• cas:526-08-9
• drugbank:DB06729
• drugcentral:2523
• hmdb:HMDB0015667
• kegg.drug:D01954
• lincs.smallmolecule:LSM-5279
• patent:US2858309
• pubmed:13873771
• pubmed:18845175
• pubmed:22785021
• pubmed:24519941
• pubmed:9864343
• reaxys:308518
• wikipedia.en:Sulfaphenazole

Ontology

ChEBI  ( EBI )

Resources

CTD