Search Ontology:
ChEBI

rac-crizotinib

Term ID
CHEBI:77563
Synonyms
  • (+-)-crizotinib
  • (RS)-crizotinib
  • rac-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine
  • racemic crizotinib
Definition
A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer.
References
  • Reaxys:12134721
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from rac-crizotinib
Phenotype where environments contain rac-crizotinib
Phenotype modified by environments containing rac-crizotinib
Human Disease / Model Data
Citations