ofloxacin

Term ID

CHEBI:7731

Synonyms

• (+-)-ofloxacin
• (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• DL 8280
• DL-8280
• Exocin
• Floxin
• Gailuoxian
• HOE 280
• HOE-280
• Ocuflox
• ofloxacin
• ofloxacine
• ofloxacino
• ofloxacinum
• OFLX
• ORF 18489
• Oxaldin
• Prifloxcin
• Prifloxin
• rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
• rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• rac-ofloxacin
• racemic ofloxacin
• Tarivid
• Visiren

Definition

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

References

• cas:82419-36-1
• drugbank:DB01165
• drugcentral:1981
• hmdb:HMDB0015296
• kegg.compound:C07321
• kegg.drug:D00453
• lincs.smallmolecule:LSM-4370
• metacyc.compound:CPD-12843
• pubmed:11710934
• pubmed:11903499
• pubmed:12827054
• pubmed:15008519
• pubmed:15557076
• pubmed:16669862
• pubmed:1804789
• pubmed:19646516
• pubmed:24497308
• pubmed:24550337
• pubmed:3469159
• pubmed:3546152
• pubmed:35897550
• pubmed:36004580
• pubmed:36228398
• pubmed:36268299
• pubmed:6960805
• pubmed:7884650
• pubmed:9228220
• reaxys:3657947
• vsdb:1898
• wikipedia.en:Ofloxacin

Ontology

ChEBI  ( EBI )

Resources

CTD