ofloxacin

Term ID

CHEBI:7731

Synonyms

• (+-)-ofloxacin
• (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• DL 8280
• DL-8280
• Exocin
• Floxin
• Gailuoxian
• HOE 280
• HOE-280
• Ocuflox
• ofloxacin
• ofloxacine
• ofloxacino
• ofloxacinum
• OFLX
• ORF 18489
• Oxaldin
• Prifloxcin
• Prifloxin
• rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
• rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• rac-ofloxacin
• racemic ofloxacin
• Tarivid
• Visiren

Definition

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

References

• CAS:82419-36-1
• DrugBank:DB01165
• Drug_Central:1981
• HMDB:HMDB0015296
• KEGG:C07321
• KEGG:D00453
• LINCS:LSM-4370
• MetaCyc:CPD-12843
• PMID:11710934
• PMID:11903499
• PMID:12827054
• PMID:15008519
• PMID:15557076
• PMID:16669862
• PMID:1804789
• PMID:19646516
• PMID:24497308
• PMID:24550337
• PMID:3469159
• PMID:3546152
• PMID:35897550
• PMID:36004580
• PMID:36228398
• PMID:36268299
• PMID:6960805
• PMID:7884650
• PMID:9228220
• Reaxys:3657947
• VSDB:1898
• Wikipedia:Ofloxacin

Ontology

ChEBI  ( EBI )

Resources

CTD