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ChEBI

bromhexine

Term ID
CHEBI:77032
Synonyms
  • 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline
  • 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine
  • bromhexina
  • bromhexine
  • bromhexinum
  • Fluibron
  • N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine
Definition
A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
References
  • beilstein:2216008
  • cas:3572-43-8
  • drugcentral:402
  • kegg.drug:D07542
  • lincs.smallmolecule:LSM-3048
  • patent:BE625022
  • pubmed:20031363
  • pubmed:22027391
  • pubmed:23781460
  • pubmed:4065592
  • pubmed:7027431
  • pubmed:7027873
  • pubmed:778563
  • wikipedia.en:Bromhexine
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from bromhexine
Phenotype where environments contain bromhexine
Phenotype modified by environments containing bromhexine
Phenotype affecting bromhexine
Human Disease Model