Search Ontology:
ChEBI

ACT-132577

Term ID
CHEBI:76609
Synonyms
  • N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]sulfuric diamide
Definition
A member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from ACT-132577
Phenotype where environments contain ACT-132577
Phenotype modified by environments containing ACT-132577
Human Disease / Model Data
Citations
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