Search Ontology:
ChEBI

macitentan

Term ID
CHEBI:76607
Synonyms
  • ACT 064992
  • ACT-064992
  • ACT064992
  • macitentan
  • macitentanum
  • N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'-propylsulfuric diamide
  • OPSUMIT
Definition
A member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension.
References
  • cas:441798-33-0
  • drugcentral:4809
  • kegg.drug:D10135
  • patent:US2008233188
  • patent:WO2007119214
  • patent:WO2008026156
  • pubmed:21403842
  • pubmed:22189899
  • pubmed:22311911
  • pubmed:22348175
  • pubmed:22458347
  • pubmed:22525377
  • pubmed:22862294
  • pubmed:23068290
  • pubmed:23077657
  • pubmed:23192269
  • pubmed:23204120
  • pubmed:23353592
  • pubmed:23568224
  • pubmed:23682110
  • pubmed:23817130
  • pubmed:23830395
  • pubmed:23900878
  • pubmed:23984728
  • pubmed:23997048
  • pubmed:24122306
  • pubmed:24122797
  • pubmed:24249746
  • pubmed:24261583
  • pubmed:24297706
  • reaxys:11340634
  • wikipedia.en:Macitentan
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from macitentan
Phenotype where environments contain macitentan
Phenotype modified by environments containing macitentan
Phenotype affecting macitentan
Human Disease Model