Search Ontology:
ChEBI

5-(N,N-hexamethylene)amiloride

Term ID
CHEBI:76400
Synonyms
  • 3-amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
  • 3-Amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide
  • Hexamethylene amiloride
  • Hexamethyleneamiloride
  • HMA
  • HMA-5
Definition
A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring.
References
  • cas:1428-95-1
  • lincs.smallmolecule:LSM-2912
  • pubmed:12046895
  • pubmed:21978672
  • pubmed:22472891
  • pubmed:23205553
  • pubmed:23329732
  • pubmed:23383318
  • pubmed:23800993
  • pubmed:23841474
  • pubmed:23996609
  • reaxys:628353
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from 5-(N,N-hexamethylene)amiloride
Phenotype where environments contain 5-(N,N-hexamethylene)amiloride
Phenotype modified by environments containing 5-(N,N-hexamethylene)amiloride
Phenotype affecting 5-(N,N-hexamethylene)amiloride
Human Disease Model